AUTOPHAGIC ACTIVATION AND DECREASE OF PLASMA MEMBRANE CHOLESTEROL CONTRIBUTE TO ANTICANCER ACTIVITIES IN NON-SMALL CELL LUNG CANCER

Non-small cell lung cancer (NSCLC), an aggressive subtype of pulmonary carcinomas with high mortality, accounts for 85% of all lung cancers.Drug resistance and high recurrence rates impede the chemotherapeutic effect, making it urgent to develop new anti-NSCLC agents.Recently, we have demonstrated that para-toluenesulfonamide is a potential anti-tu